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Louisville Cardinals at SMU Mustangs: November 22, 2025

The SMU Mustangs beat the Louisville Cardinals 38-6 at Gerald J. Ford Stadium on November 22, 2025 (2025 season).

Final · Played November 22, 2025 · Updated October 14, 2026 at 8:06 AM ET · StatsNext box-score records

Most passing yards: Kevin Jennings (SMU Mustangs, 303). Most rushing yards: Duke Watson (Louisville Cardinals, 36); Chris Johnson Jr. (SMU Mustangs, 19). Most receiving yards: Nate Kurisky (Louisville Cardinals, 5); Yamir Knight (SMU Mustangs, 44).

Line score

TeamQ1Q2Q3Q4Final
Louisville Cardinals33006
SMU Mustangs71431438

Team comparison

Team statsLOUSMU
Passing yards100307
Rushing yards128178
Rushing attempts3036
Completions1430
Pass attempts2038
Interceptions thrown10
Sacks12

What stood out

  • Passing yards: Louisville Cardinals 100, SMU Mustangs 307.
  • Rushing yards: Louisville Cardinals 128, SMU Mustangs 178.
  • The SMU Mustangs' biggest edge came in the 4th quarter (14-0).

Player lines

Lines for players with a StatsNext page; other players’ lines are in the app.

Head-to-head

No earlier meeting between these teams is in their stored recent results.

Full SMU Mustangs vs Louisville Cardinals head-to-head (2 meetings).

About this page

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