Louisville Cardinals vs SMU Mustangs: head-to-head
The Louisville Cardinals and SMU Mustangs have met 2 times in StatsNext’s stored College football results, from November 22, 2025 to September 19, 2026 (2 seasons). The series is level at 1-1.
Series summary
| Meetings | Games | LOU wins | SMU wins | LOU points/g | SMU points/g | Total points/g |
|---|---|---|---|---|---|---|
| All meetings | 2 | 1 | 1 | 23.5 | 34.5 | 58 |
| At LOU | 1 | 1 | 0 | 41 | 31 | 72 |
| At SMU | 1 | 0 | 1 | 6 | 38 | 44 |
Every stored meeting
| Date | Season | Venue | Score | Winner | Margin | Total |
|---|---|---|---|---|---|---|
| Sep 19, 2026 | 2026 | At LOU | LOU 41, SMU 31 | LOU | 10 | 72 |
| Nov 22, 2025 | 2025 | At SMU | LOU 6, SMU 38 | SMU | 32 | 44 |
What stands out
- Largest Louisville Cardinals win in these meetings: 41-31 on Sep 19, 2026.
- Largest SMU Mustangs win: 38-6 on Nov 22, 2025.
- Highest combined score: 72 points (Sep 19, 2026); lowest: 44 (Nov 22, 2025).
- Average margin: 21 points per meeting.
How to read this
- These are the final scores of the meetings stored in StatsNext (the 2 most recent, up to 30). Older meetings may not be in these records.
- Rosters, coaches and venues change between seasons, and a few meetings are a small sample: past results describe what happened, not what will happen.
- Scores are final scores.
This page contains no sportsbook prices or betting lines.
Keep researching
- Louisville Cardinals stats and results
- SMU Mustangs stats and results
- All College football head-to-head pages