Cardinals at 49ers: September 27, 2026
The San Francisco 49ers beat the Arizona Cardinals 36-30 at Levi's Stadium on September 27, 2026 (2026 regular season).
Most passing yards: Jacoby Brissett (Cardinals, 280); Brock Purdy (49ers, 297). Most rushing yards: Jeremiyah Love (Cardinals, 90); Christian McCaffrey (49ers, 75). Most receiving yards: Michael Wilson (Cardinals, 89); George Kittle (49ers, 82).
On this page
Scoring by quarter
| Team | Q1 | Q2 | Q3 | Q4 | Final |
|---|---|---|---|---|---|
| Arizona Cardinals | 0 | 6 | 7 | 17 | 30 |
| San Francisco 49ers | 7 | 10 | 6 | 13 | 36 |
Team comparison
| Team stats | ARI | SF |
|---|---|---|
| Total yards | 365 | 437 |
| Passing yards | 272 | 297 |
| Rushing yards | 93 | 140 |
| First downs | 27 | 23 |
| Yards per play | 4.5 | 8.7 |
| Turnovers | 0 | 1 |
| Penalty yards | 86 | 69 |
| Red zone (scores/trips) | 3/5 | 2/2 |
What stood out
- The 49ers out-gained the Cardinals 437 to 365 total yards.
- Turnovers: Cardinals 0, 49ers 1.
- The 49ers' biggest scoring edge came in the 1st quarter (7-0).
- The 49ers ran for 140 yards to the Cardinals' 93.
Featured player lines
- Jacoby Brissett (ARI QB): 38 CMP, 52 ATT, 280 PASS YDS, 2 PASS TD, 0 INT, 4 CAR, 4 RUSH YDS
- Jeremiyah Love (ARI RB): 21 CAR, 90 RUSH YDS, 0 RUSH TD, 5 TGT, 5 REC, 19 REC YDS
- Tyler Allgeier (ARI RB): 2 CAR, -1 RUSH YDS, 0 RUSH TD, 4 TGT, 4 REC, 10 REC YDS
- Jalen Brooks (ARI WR): 1 TGT, 0 REC, 0 REC YDS, 0 REC TD
- Kendrick Bourne (ARI WR): 3 TGT, 2 REC, 22 REC YDS, 0 REC TD
- Marvin Harrison Jr. (ARI WR): 5 TGT, 3 REC, 40 REC YDS, 0 REC TD
- Michael Wilson (ARI WR): 17 TGT, 11 REC, 89 REC YDS, 1 REC TD
- Elijah Higgins (ARI TE): 3 TGT, 3 REC, 20 REC YDS, 0 REC TD
- Hunter Long (ARI TE): 1 TGT, 1 REC, 5 REC YDS, 0 REC TD
- Trey McBride (ARI TE): 11 TGT, 9 REC, 75 REC YDS, 0 REC TD
- Brock Purdy (SF QB): 15 CMP, 27 ATT, 297 PASS YDS, 4 PASS TD, 0 INT, 2 CAR, 34 RUSH YDS
- Christian McCaffrey (SF RB): 15 CAR, 75 RUSH YDS, 1 RUSH TD, 5 TGT, 4 REC, 41 REC YDS
- Kaelon Black (SF RB): 4 CAR, 17 RUSH YDS, 0 RUSH TD, 1 TGT, 0 REC, 0 REC YDS
- Deebo Samuel Sr. (SF WR): 0 TGT, 0 REC, 80 REC YDS, 1 REC TD
- Jacob Cowing (SF WR): 2 TGT, 0 REC, 0 REC YDS, 0 REC TD
- Mike Evans (SF WR): 6 TGT, 3 REC, 34 REC YDS, 1 REC TD
- George Kittle (SF TE): 7 TGT, 6 REC, 82 REC YDS, 2 REC TD
- Luke Farrell (SF TE): 1 TGT, 0 REC, 0 REC YDS, 0 REC TD
Player pages exist for the players listed; other players' lines are in StatsNext.
Head-to-head
| Date | Result |
|---|---|
| November 16, 2025 | SF 41, ARI 22 (at Arizona) |
| September 21, 2025 | ARI 15, SF 16 (at San Francisco) |
| January 5, 2025 | SF 24, ARI 47 (at Arizona) |
| October 6, 2024 | ARI 24, SF 23 (at San Francisco) |
| December 17, 2023 | SF 45, ARI 29 (at Arizona) |
Full 49ers vs Cardinals head-to-head (11 meetings).
About this page
This game is final; the statistics on this page change only if a stored box score is corrected. Team statistics are each team's own box score for this game.
This page shows box-score statistics and results only. It contains no sportsbook prices or betting lines. Current markets, hit rates against the line and StatsNext research are in the app.
Research in StatsNext
- This game in StatsNext: Matchup Research for both teams
- Arizona Cardinals stats and results
- San Francisco 49ers stats and results
- Cardinals' previous game: Seahawks at Cardinals, September 20, 2026
- Cardinals' next game: Cardinals at Giants, October 4, 2026
- 49ers' previous game: Dolphins at 49ers, September 20, 2026
- 49ers' next game: Broncos at 49ers, October 4, 2026
- All completed NFL games
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